Calreticulin兔單克隆抗體

價(jià)格￥1000
規(guī)格100ul
貨號(hào)HKZ150425
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價(jià)
HaoKebio	HKZ150425	Calreticulin兔單克隆抗體	100ul	支	1000

Calreticulin
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50302?Clone# ?BP6279
Predicted?Molecular Wt:
48kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P27797
Background:
Calcium?is a?universal signaling?molecule?involved?in?many cellular functions, such?as?cell?motility,?metabolism,?protein
modification, et al.?Calcium?is stored?in the endoplasmic?reticulum?(ER),?where?it?is?buffered?by?calcium?binding?chaperones?such as calnexin and calreticulin.?Calreticulin?also functions?asan?ER?chaperone?that?ensures?proper?folding?and?quality
control of?newly synthesized glycoproteins.
Calreticulin?is expressed?in all?kinds of?normal tissues and?tumor?tissues.
Calreticulin?purified from tumor can stimulate the anti-tumor?immune?response?of the?body,?the?possible?mechanism?is?that???the calreticulin?molecule?binds to the tumor?antigen?polypeptide, and?in the?process?of?calreticulinto?the?cell?membrane,?the?tumor antigen?peptide?bound with?it?is?brought to the cell?membrane and?presented?to?the?antigen-presenting?cell,?thus
stimulating the anti-tumor?immune effect of the?body. Calreticulin?purified?from?tumor?can?stimulate?the?anti-tumor?immune??response of the?body, the?possible?mechanism?is that the calreticulin?molecule?binds to the tumor?antigen?polypeptide,?and?in?the?process of calreticulinto the cell?membrane, the tumor?antigen?peptide?bound with?it?is?brought?to?the?cell?membrane
and?presented to the antigen-presenting cell, thus stimulating the?anti-tumor?immune?effect?of the?body.
Subcellular?location:
Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Groenendyk, J. et?al.?(2004)?Mol?Cells?17,?383-9.
2.?Williams,?D.B.?(2006) J?Cell?Sci?119,?615-23.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of ?human?prostate?labelling Calreticulin?with???BP6279.

HKZ150425_BP6279_Calreticulin 下載

暫無