Cytokeratin 19兔單克隆抗體

價格￥600
規(guī)格100ul
貨號HKZ150140
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150140	Cytokeratin 19兔單克隆抗體	100ul	支	600

Cytokeratin?19
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
?
Catalog# ?50017?Clone# ?BP6022
?
Predicted?Molecular Wt:
44kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P08727

Background:
Cytokeratin?19?is the smallest?keratin and?is exceptional since?it?widely?lacks the?non–helical?tail?domain?typical?for?all?other?keratins.?It?may?have evolved from?keratinocyte?keratins.
?
Cytokeratin?19?is expressed?in?most simple epithelia?(excluding?parenchymatous cells?such?as?hepatocytes,?pancreatic?acinar
cells, and?renal?proximal tubular cells),?notably?in various ductal?epithelia,?in?small?and?large?intestinal?epithelium,?in?gastric
foveolar epithelium, and?in?mesothelium.?Furthermore,?it?is?present?in?most cells of?pseudostratified?epithelia?and?urothelium???as well as?in?basal cells of?non-keratinizing stratified?squamous?epithelium.?In?carcinomas,?cytokeratin?19?is?widely?expressed?in?both adenocarcinomas and squamous cell?carcinomas?and therefore?is?not?extensively?used?as?an?immunohistochemical
marker for carcinoma?subtyping.
?
Cytokeratin?19?is?not expressed?in?most?hepatocytes, therefore cytokeratin?19?is?useful?in the?identification of?liver?metastasis?and can?be?used?in a?panel with?Hepatocyte Specific?Antigen.
?

Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to cytokeratin?19
residues?within?aa1‐100 of?cytokeratin?19?was?used?as an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of?human?thyroid cancer tissue
labelling?cytokeratin?19?with?BP6022.?Heat
mediated?antigen?retrieval?was?performed?using
Tris/EDTA?buffer?pH?9.0
Background?References: