Neurofilament鼠單克隆抗體

價格￥600
規(guī)格100ul
貨號HKZ150372
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150372	Neurofilament鼠單克隆抗體	100ul	支	600

Neurofilament
Mouse?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50249???Clone# ?BPM6226
Predicted?Molecular Wt:
102kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P07197
Background:
Neurofilaments are the?major?intermediate filaments found?in?neurons and consist?of?light?(NFL),?medium?(NFM),and?heavy?(NFH) subunits. Similar?in structure to other?intermediate filament?proteins,?neurofilaments?have?a?globular?amino-terminal??head, a central α-helical?rod domain,?and?a?carboxy-terminal?tail.?A?heterotetrameric?unit?(NFL-NFM?and?NFL-NFH)?forms?a????protofilament, with eight?protofilaments comprising the typical?10?nm?intermediate filament.
Research studies?have shown?neurofilament accumulations?in?many?human?neurological disorders?including?Parkinson’s
disease?(in?Lewy?bodies along with α-synuclein), Alzheimer’s disease,?Charcot-Marie-Tooth?disease,?and Amyotrophic?Lateral?Sclerosis?(ALS).
Neurofilament antibody?mainly stains?neurons?in tissue sections of?brain?and?other?tissues.?Neurofilament?has?been?shown?to?react with?neuroblastomas, gangliomas,?pheochromocytomas,?Merkel cell tumors and carcinoid?tumors.
Subcellular?location:
Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:Recombinant full-length?protein correspongding to?human?Neurofilament.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?Franquemont?DW, et?al. Am?J?Clin?Pathol?1994 Aug;102(2):163-70.
2. ?Diepholder?HM, et?al.?Cancer?1991?Nov?15;68(10):2192-201.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-?embedded?sections)?analysis?of?brain?labelling
Neurofilament?with?BPM6226.

HKZ150372_BPM6226_Neurofilament 下載

暫無