MHC Ⅱ(DR α chain)兔單克隆抗體

價(jià)格￥1800
規(guī)格100ul
貨號HKZ150315
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價(jià)
HaoKebio	HKZ150315	MHC Ⅱ(DR α chain)兔單克隆抗體	100ul	支	1800

MHC?Ⅱ(DR?α?chain)
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50192?Clone# ?BP6170
Predicted?Molecular Wt:
29kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P01903
Background:
Major?histocompatibility complex class?II?(MHC class?II)?molecules are?heterodimeric, transmembrane?glycoproteins?expressed
on the surface of antigen-presenting cells?such?as?macrophages,?dendritic?cells,?and?B?cells.?Expression?can?also?be?induced?on?other cell types through?interferon-γ signaling.?Prior to?being displayed?on?the?cell?membrane,?MHC?class?II?molecules?are
loaded with exogenous?peptide antigens approximately?15-24 amino?acids?in?length?that?were?derived?from?endocytosed?extracellular?proteins digested?in the?lysosome. Antigen-presentation through?MHC class?II?is?required for T?cell?activation?during the?immune?response to extracellular?pathogens.?In?humans, the?MHC class?II?protein complex?is?encoded?by?the????human?leukocyte antigen gene complex?(HLA).
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide?near?N-terminal?residues?in?Human?MHC?Ⅱ(DR?α chain) was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Temponi,?M. et?al. J?Immunol?Methods?161?(1993)?.
2.?Ting, J.P. and?Trowsdale, J. Cell?109?Suppl?(2002)?.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of?human?colorectal?carcinoma tissue
labelling?DR?α chain?of
MHC?Ⅱ with?BP6170.?Heat mediated?antigen?retrieval??was?performed?using
Tris/EDTA?buffer?pH?9.0

HKZ150315_BP6170_MHC Ⅱ(DR α chain)下載

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