TRPS1兔單克隆抗體

價格￥1800
規(guī)格100ul
貨號HKZ150377
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150377	TRPS1兔單克隆抗體	100ul	支	1800

TRPS1
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50254?Clone# ?BP6231
Predicted?Molecular Wt:
141kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q9UHF7
Background:
TRPS1?is a transcription factor that was?initially discovered?as?being?mutated?in Tricho-rhino-phalangeal?syndrome,?a
craniofacial and skeletal?malformation syndrome. TRPS1?recognizes GATA?sequences?and?represses the?activation?potential?of?other GATA factors.?In addition, TRPS1?binds to the?NuRD?complex via?CHD4?and?can?repress?other?key transcription?factors
such asp63 and?estrogen?receptor.
TRPS1?is?highly expressed?in?breast cancer, cervix, esophageal?epithelium.
TRPS1?is?used as a sensitive and?specific?marker?of?breast?cancer?in?pathological?diagnosis.
Subcellular?location:
Nucleus
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Recombinant?protein fragment of TRPS1 was?used as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Serandour, A.A. et?al.?(2018) Oncogene?37,?5281-91.
2.?Wang, Y. et?al.?(2018)?Oncogenesis?7,?96.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-????embedded?sections)?analysis of?breast cancer?labelling?TRPS1 with?BP6231.

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