一抗 抗體 試劑 SOX11兔單克隆抗體一抗 抗體 試劑 價格￥1000規(guī)格100ul貨號HKZ150188單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價HaoKebioHKZ150188SOX11兔單克隆抗體100ul支1000SOX11Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50065?Clone# ?BP6070Predicted?Molecular Wt:47kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P35716Background:SOX11?(SOX = SRY-related?HMG?box)?is a?nuclear transcription factor?belonging to?subgroup?C?of?SRY?(sex?determining?region?on Y-chromosome)?related?HMG?(high?mobility group)?box genes.?It contains 2?functional?domains: A?HMG?box?DNA-binding??domain,?located at the?N-terminus, and a transactivation?domain?(TAD),?located?at?the?C-terminus.SOX11 expression?is critical for embryonic?neurogenesis and?tissue?remodeling,?it?is?normally?expressed?during?the?developing?nervous system of?human?embryos and?is?required for?neurite growth?and?neuron?survival.?Expression?is?seen?in fetal?tissues????(18-25 weeks)?mainly?in?the?brain. Outside?the?CNS?SOX11?seems?primarily?to?be?expressed?at?sites?of?epithelial-mesenchymal interactions. SOX11?is?not expressed?in?normal adult?human tissues,?and?its?over-expression?is?reported?in?over?90%?of?mantle?cell?lymphomas?(MCL),?including the?rare cyclin?D1?negative cases.Currently the only diagnostic application?is verification?of?mantle?cell?lymphomas,?particularly the?rare?cyclin?D1?negative?cases.Subcellular?location:NucleusRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding to SOX11?residueswithin?aa300-400 of??SOX11?was?used?as?an immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Background?References:1.?Chen?Y-H?etal.?Mod.?Pathol. 2010;23(1):105–12.2. ?Mozos?A?et?al.?Haematologica.?2009;94(11):1555–1562.Immunohistochemistry?(Formalin/PFA-fixedparaffin-embeddedsections analysis?ofmantle?zone celllymphoma tissuelabelling?SOX11?withBP6070.?Heat?mediated antigen?retrieval?wasperformed?usingTris/EDTA?buffer?pH?9.0 HKZ150188_BP6070_ SOX11下載 暫無 說明文檔下載說明書.pdf 上一篇: CD35兔單克隆抗體下一篇: TPO兔單克隆抗體 推薦 SF-1兔單克隆抗體 2024年5月23日 1143 暫無 查看全文 PASM 六胺銀染液 2024年10月9日 1262 暫無 查看全文 Edu染色試劑盒（綠，AF488) 2023年7月12日 1091 【使用方法】 動物 EdU 注射 對于小鼠，可以按照 10-200mg/kg 的用量，把 EdU 用 PBS 配制成一定濃度，腹... 查看全文 蘇木素分化液 2024年9月14日 1338 2.為了您的安全和健康，請穿實驗服并戴一次性手套操作。 暫無 查看全文 您好！請登錄 點擊取消回復(fù) 請登錄后評論 點擊這里取消回復(fù)。
Edu染色試劑盒（綠，AF488) 2023年7月12日 1091 【使用方法】 動物 EdU 注射 對于小鼠，可以按照 10-200mg/kg 的用量，把 EdU 用 PBS 配制成一定濃度，腹... 查看全文
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