CD1a兔單克隆抗體

價格￥1000
規(guī)格100ul
貨號HKZ150173
單位支
品牌HaoKebio

產品介紹

產品參數

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150173	CD1a兔單克隆抗體	100ul	支	1000

CD1a
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50050?Clone# ?BP6055
Predicted?Molecular Wt:
37kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P06126
Background:
CD1a?is?a?member?of?the?family?group?1 CD1?proteins?(CD1a,?CD1b,?and?CD1c),?which?share?the?capacity?to?present?microbial lipid antigens to?T?cells.
CD1a?is expressed?predominantly on?Langerhans cells?(LCs),?it can?be?expressed?by T-cells?under?certain?conditions.?Immature
thymocytes express CD1a, as do?some T-cells?involved?in?neoplastic?conditions?such?as?pre-lymphoblastic?lymphomas/leukemias and follicular dendritic cell?sarcoma.
CD1a expression?on?pathogenic?Langerhans cells?(LCs)?in?LCH?is?regarded as a?hallmark?of this?disease?and?may?as?a?potential?target for future therapeutic strategies against?inflammatory skin?diseases.
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to CD1a?residues?????within?aa1-100 of?CD1a?was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ?Hunger?RE, et.al, J?Clin?Invest.?2004?Mar;113(5):701-8.
2.?Ji?Hyung?Kim, et.al,?Nature?Immunology?17
(10) ,?pp.?1159-1166.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of
esophagus tissue
labelling CD1a?with
BP6055.?Heat?mediated antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0

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