Positive IHC detected in: human breast cancer tissue Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0
Positive FC detected in: HeLa cells
Recommended dilution: WB : 1:1000-1:4000 IHC : 1:100-1:400 Product Information
Storage: 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C.?Aliquoting is unnecessary for -20oC storage. Immunogen Information
Immunogen: Peptide
Full name: cyclin-dependent kinase 3
Calculated molecular weight: 35 kDa
Observed molecular weight: 40-45 kDa
Gene symbol CDK3
Synonyms CDK3, Cell division protein kinase 3, cyclin dependent kinase 3 Background CDK3 belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It is probably involved in the control of the cell cycle. CDK3 interacts with a yet unknown type of cyclin. It can phosphorylate histone H1. Endogenous Cyclin C/Cdk3 complexes are critical to promote exit from quiescence in an Rb-dependent manner. Cyclin C/Cdk3 complexes is a key regulators of cell cycle reentry in human cells. (PMID: 15130482 )The antibody is specific to CDK3.
杭州浩克生物
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