c-Met (Cytoplasmic)兔多克隆抗體

價格￥2800
規(guī)格200ul
貨號HK210105L
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HK210105L	c-Met (Cytoplasmic)兔多克隆抗體	200ul	支	2800

Applications

Tested Applications:
IHC, IP, WB,ELISA
Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human, canine, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, MDCK cells, HepG2 cells, A431 cells, rat liver tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human breast cancer tissue, human colon tissue, human liver cancer tissue
Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
Product Information

Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20^oC storage.
Immunogen Information

Full name:
met proto-oncogene (hepatocyte growth factor receptor)

Calculated molecular weight:
1390 aa, 155 kDa

Observed molecular weight:
145 kDa

Gene symbol
MET

Synonyms
AUTS9, c-Met, HGF receptor, HGF/SF receptor, HGFR, MET, Proto oncogene c Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine protein kinase Met
Background
c-Met (also named as MET or HGFR) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to HGF ligand. c-Met regulates many physiological processes including proliferation, scattering, morphogenesis and survival. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Overexpression and/or mutation of c-Met has been reported in various human malignancies, including lung cancer, breast cancer, head and neck cancer, gastric cancer, colorectal cancer, bladder cancer, uterine cervix carcinoma, and esophageal carcinoma, c-Met could serve as an important therapeutic target (PMID: 26036285). The c-met receptor is a 190-kD glycoprotein consisting of a 145-kD membrane-spanning beta chain and a 50-kD alpha chain (PMID: 7806559). In Western blot, this antibody produces bands of unknown identity at 55 and 100 kDa.

暫無

說明文檔下載

說明書.pdf

上一篇: COX5A兔多克隆抗體下一篇: CDK6兔多克隆抗體

普通病理

分子病理

成像分析

分子生物

理化檢測

蛋白生物學(xué)

細(xì)胞實驗

普通形態(tài)

分子病理

分子生物學(xué)

抗體

蛋白質(zhì)生物學(xué)

c-Met (Cytoplasmic)兔多克隆抗體

說明文檔下載

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