Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage. Immunogen Information
Full name: fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Calculated molecular weight: 17 kDa
Observed molecular weight: 17 kDa
Gene symbol FIS1
Synonyms CGI 135, FIS1, FIS1 homolog, hFis1, TPR repeat protein 11, TTC11 Background Fis1 (fission 1) is an integral mitochondrial outer membrane protein that participates in mitochondrial fission by interacting with dynamin-related protein 1 (Drp1). Excessive mitochondrial fission is associated with the pathology of a number of neurodegenerative or neurodevelopmental diseases. Increased expression of Fis1 has been found in Huntington’s disease (HD)-affected brain, Alzheimer’s disease (AD) patients, and autism spectrum disorder. This antibody was raised against the full-length of human Fis1 protein, and recognizes endogenous Fis1 protein in various lysates. (PMID: 21257639, 21459773, 23333625)
杭州浩克生物
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